Document Type : Original Articles

Abstract

Introduction: Intravenous sedation is one of methods to control anxiety in dentistry. However, due to intravenous use of potent drugs, the odds of hypoxia increases. In this study the prevalence of this complication between the two intravenous sedation methods was investigated. Materials and Methods: In this double-blind prospective clinical trial a total of 73 implant patients were evaluated in two groups. Conscious sedation was administered with a combination of midazolam/fentanyl in one group and with midazolam/ketamine in the other. SPO2 was measured in 6 stages and results were analyzed with t-test using SPSS software (α = 0.05). Results: Mean of SPO2 five minutes after drug injection decreased in both groups. In midazolam/fentanyl group it decreased to 93.2% and in midazolam/ketamine group to 94.9% which indicates that the decrease in SPO2 in the first group (midazolam/fentanyl) was significantly more than other group. Conclusion: Use of intravenous sedation resulted in a decrease in SPO2 five minutes after sedation. In the midazolam/fentanyl group, it decreased to 93.2% and in the midazolam/ketamine group it decreased to 94.9%, with a significantly higher decrease in the former.   Key words: Dental implant, Fentanyl, Ketamine, Intravenous sedation, Midazolam.