Document Type : مقالههای پژوهشی
Authors
1 Assistant Professor, Deportment of Oral and Maxillofacial Pathology, School of Dentistry, Islamic Azad University of Isfahan (Khorasgan) Branch, Isfahan, Iran.
2 Assistant Professor, Deportment of Periodontics, School of Dentistry, Islamic Azad University of Isfahan (Khorasgan) Branch, Isfahan, Iran.
3 Dentist, Isfahan, Iran.
4 Postgraduate Student, Deportment of Periodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Abstract
Introduction: Diabetes mellitus and chronic periodontitis are common worldwide disorders and since periodontal diseases are more common and more severe in diabetic patients, the aim of present study was to investigate the relationship between HbA1C serum levels and chronic periodontitis.
Materials & Methods: In this case‒control, descriptive/analytical study, the HbA1C levels were evaluated in 55 subjects, 35‒45 years of age, in two groups with and without periodontitis, who were healthy otherwise. Thirty subjects had chronic periodontitis (PPD > 2 mm) and 25 subjects had healthy gingiva. HbA1C levels were determined by means of Ichroma equipment. Data were analyzed with independent t-test using SPSS 18 (α = 0.05).
Results: Independent t-test showed significantly higher serum levels of HBA1C in patients with periodontitis compared to healthy subjects (p value = 0.021).
Conclusion: Based on the results of the present study, inflammation in chronic periodontitis disturbs the metabolism of glucose, possibly resulting in periodontitis in the long term. Therefore, a definitive diagnosis and treatment of chronic periodontitis along with proper oral health is emphasized.
Key words: Chronic periodontitis, Diabetes mellitus, Glycosylated hemoglobin.