Journal of Isfahan Dental School

Prevalence of HSV-1 Virus in Periodontal Pockets in Patients with Chronic Periodontitis in Qom, Iran

Document Type : مقاله‌های پژوهشی

Authors

1 Graduate, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.

2 Post Graduate, Department of Microbiology, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.

3 Department of Periodontics, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.

4 Post Graduate, Department of Microbiology, Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran.

Abstract

Introduction: Periodontitis is an inflammatory disease of the tooth-supporting tissues that is caused by specific microorganisms, which results in degeneration of the periodontal ligament and alveolar bone and causes gingival recession. In recent years some evidence has emerged on the relationship between human herpes virus and periodontal diseases. The aim of the present study was to evaluate the presence of HSV-1 virus in periodontal pockets of subjects with chronic periodontitis in Qom, Iran.
Materials & Methods: In this descriptive cross-sectional study, 92 subjects with chronic periodontitis were collected from Hakim and Ali-ibn Abi-Talib Clinics in Qom in 2016-17. Real-time PCR technique was used to evaluate HSV-1 infection of patient samples. Data were analyzed with SPSS version 20 in terms of the relationship between age, sex and intensity of chronic periodontitis and the incidence of HSV (α = 0.05).
Results: In this study, three cases (3.3%) of HSV were found in subjects with chronic periodontitis. There was no relationship between chronic periodontitis, age and sex and HSV-1.
Conclusion: The results of this study suggest further screening techniques and more accurate techniques to detect HSV-1 and larger sample sizes to clarify the role of HSV-1 in the pathogenesis of chronic periodontitis.
Key words: Chronic periodontitis, Herpes virus-1, Real-Time PCR.

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Journal of Isfahan Dental School
Volume 14, Issue 4 - Serial Number 4
October 2018
Pages 359-365