مجله دانشکده دندان‌پزشکی اصفهان

اثر داروهای مایع خوراکی در کودکان بر قدرت باند برشی کامپوزیت در دندان‌های شیری

نوع مقاله : مقاله‌های پژوهشی

چکیده

مقدمه: با توجه به شیوع مصرف داروهای مایع خوراکی در کودکان و با توجه به این‌که در مطالعات متعدد مشخص شده که داروهای مایع کودکان بر ساختار مینای دندان مؤثر هستند و باندینگ کامپوزیت وابسته به ساختار مینا است، لذا هدف از انجام این مطالعه، بررسی اثر داروهای مایع خوراکی مورد استفاده در کودکان بر قدرت باند کامپوزیت با مینای دندان کانین شیری بود.
مواد و روش ها: در این مطالعه‌ی تجربی- آزمایشگاهی، 90 دندان کانین شیری به 9 گروه (8 گروه دارو و 1 گروه شاهد) تقسیم شدند. هر گروه 10تایی از دندان‌ها 3 بار در روز به مدت 1 دقیقه در 10 میلی‌لیتر از داروی مورد نظر غوطه‌ور شدند. بعد از 7 و 14 روز، 5 دندان از هر گروه با کامپوزیت باند شده و استحکام باند برشی آن‌ها اندازه‌گیری شد. جهت تحلیل داده‌ها از آزمون‌های آماری ANOVA، Paired T- test و Pearson استفاده و سطح معنی‌داری 0/05 = α در نظر گرفته شد.
یافته ها: در همه‌ی گروه‌ها در مقایسه با گروه شاهد میانگین استحکام باند برشی در هفته‌ی اول و دوم تفاوت معنی‌داری نداشت (0/05 < p value). همچنین بین میانگین استحکام باند برشی کامپوزیت در هیچ یک از 8 گروه در هفته‌های اول و دوم اختلاف معنی‌داری وجود نداشت (0/05 < p value).
نتیجه گیری: بر اساس این مطالعه، استفاده‌ی کوتاه‌مدت از داروهای مورد بررسی باعث ایجاد تغییرات معنی‌دار در استحکام باند برشی کامپوزیت به مینا نگردید.
کلیدواژه ها: دندان شیری؛ استحکام برشی؛ رزین کامپوزیت.

عنوان مقاله [English]

Effects of Oral Liquid Medicaments in Children on Shear Bond Strength of Resin Composite in Primary Teeth

چکیده [English]

Introduction: Due to the prevalence of the use of  oral liquid medications in children with chronic diseases (asthma, heart problems, seizures and kidney problems) and also in children with transient diseases (influenza, colds, tonsillitis, ear infections, sinusitis and seasonal allergy) and due to the fact that several studies have shown that children’s' common medications affect topography and enamel structure, and composite bonding is dependent on enamel structure, the aim of this study was to investigate the effect of oral liquid medications used in children on composite bond strength to primary canine dental enamel.
Methods and materials: In this experimental-laboratory study, 90 teeth were divided into 9 groups, 8 drug groups and 1 control group (artificial saliva). Each group of 10 teeth was immersed 3 times a day for 1 minute in 10 ml of the desired drug. After 7 days and after 14 days, 5 teeth from each group were bonded with composite and their shear bond strengths were measured. Data were analyzed by one-way ANOVA, paired T-test and Pearson correlation coefficient tests. (α = 0.05).
Results: In all groups, in comparison with the control group, the mean bond strength was not significantly different in the first and second weeks (p value > 0.05). Also, there was no significant difference between the mean composite shear bond strengths in each of the nine groups in the first and second weeks (p value > 0.05). Pearson correlation coefficient showed that there was no significant relationship between PH value with shear bond strength of composite in first weeks (p value = 0.53) and second (p value = 0.83).
Conclusion: Based on this study, short-term use (up to 14 days) of medications did not significantly change the shear bond strength of the composite to enamel.
Keywords: Primary teeth; Shear strength; Composite resins.

1. Babu KL, Rai K, Hedge AM. Pediatric liquid medicaments–do they erode the teeth surface? An in vitro study: part I. J Clin Pediatr Dent 2008; 32(3): 189-94.
2. Tupalli AR, Satish B, Shetty BR, Battu S, Kumar JP, Nagaraju B. Evaluation of the erosive potential of various pediatric liquid medicaments: an in-vitro study. J Int Oral Health 2014; 6(1): 59-65.
3. Nunn JH, Ng SK, Sharkey I, Coulthard M. The dental implications of chronic use of acidic medicines in medically compromised children. Pharm World Sci 2001; 23(3): 118-9.
4. Subramaniam P, Nandan N. Cariogenic potential of pediatric liquid medicaments-An in vitro study. J Clin Pediatr Dent 2012; 36(4): 357-62.
5. Cury JA, Tenuta LM. Enamel remineralization: controlling the caries disease or treating early caries lesions? Braz Oral Res 2009; 23(Suppl 1): 23-30.
6. Lussi A, Schlüter N, Rakhmatullina E, Ganss C. Dental erosion–an overview with emphasis on chemical and histopathological aspects. Caries Res 2011; 45(Suppl 1): 2-12.
7. Cavalcanti AL, de Sousa RI, Clementino MA, Vieira FF, Cavalcanti CL, Xavier AF. In vitro analysis of the cariogenic and erosive potential of paediatric antitussive liquid oral medications. Tanzan J Health Res 2012; 14(2): 139-45.
8. Valinoti AC, Pierro VS, Da Silva EM, Maia LC. In vitro alterations in dental enamel exposed to acidic medicines. Int J Paediatr Dent 2011; 21(2): 141-50.
9. Xavier AF, Moura EF, Azevedo WF, Vieira FF, Abreu MH, Cavalcanti AL. Erosive and cariogenicity potential of pediatric drugs: study of physicochemical parameters. BMC Oral Health 2013; 13(1): 71.
10. Nankar M, Walimbe H, Ahmed Bijle MN, Kontham U, Kamath A, Muchandi S. Comparative evaluation of cariogenic and erosive potential of commonly prescribed pediatric liquid medicaments: an in vitro study. J Contemp Dent Pract 2014; 15(1): 20-5.
11. Soares DN, Antonio AG, Pierro VS, Iorio NL, dos Santos KR, Maia LC. In vitro effect of paediatric liquid medicines on deciduous enamel exposed to biofilm. Acta Odontol Scand 2013; 71(5): 1136-41.
12. Dean J, McDonald RE. McDonald's and Avery's dentistry for the child and adolescent. 10th ed. St. Louis: Mosby; 2016.
13. Valinoti AC, Neves BG, de Silva EM, Maia LC. Surface degradation of composite resins by acidic medicines and pH-cycling. J Appl Oral Sci 2008; 16(4): 257-65.
14. Xavier AF, de Abreu MH, Anselmo GC, Cavalcanti AL. Changes in microhardness and morphology of the adamantine structure as a function of the exposure time to different drugs. Pesqui Bras em Odontopediatria Clin Integr 2015; 15(1): 279-89.
15. Mittal S, Singh BP, Sharma AK, Mittal K, Justa A, Vaid P. Surface changes of primary tooth enamel by commonly used pediatric liquid medicaments: A scanning electron microscope study. J Pediatr Dent 2017; 5(1): 14-20.
16. Low IM, Duraman N, Mahmood U. Mapping the structure, composition and mechanical properties of human teeth. Mater Sci Eng: C 2008; 28(2): 243-7.
17. Amaechi BT, Higham SM, Edgar WM. Factors influencing the development of dental erosion in vitro: enamel type, temperature and exposure time. J Oral Rehabil 1999; 26(8): 624-30.
18. Nadin G, Goel BR, Yeung CA, Glenny AM. Pulp treatment for extensive decay in primary teeth. Cochrane Database Syst Rev 2003; (1): CD003220.
19. Burke FJT, Fleming GJP, Owen FJ, Watson DJ. Materials for restoration of primary teeth: 2. Glass ionomer derivatives and compomers. Dent update 2002; 29(1): 10-7.
20. Donly KJ, Garcia-Godoy F. The use of resin-based composite in children. Pediatr Dent 2002; 24(5): 480-8.
21. Swanson TK, Feigal RJ, Tantbirojn D, Hodges JS. Effect of adhesive systems and bevel on enamel margin integrity in primary and permanent teeth. Pediatr Dent 2008; 30(2): 134-40.
22. Abdelmegid FY. Effect of whitening toothpastes on bonding of restorative materials to enamel of primary teeth. Niger J Clin Pract 2016; 19(2): 242-7.
23. Sharafeddin F, Farshad F. The effect of aloe vera, pomegranate peel, grape seed extract, green tea, and sodium ascorbate as antioxidants on the shear bond strength of composite resin to home-bleached enamel. J Dent (Shiraz) 2015; 16(4): 296-301.
24. Rizvi A, Zafar MS, Al-Wasifi Y, Fareed W, Khurshid Z. Role of enamel deminerlization and remineralization on microtensile bond strength of resin composite. Eur J Dent 2016; 10(3): 376-80.
25. Peres KG, Oliveira CT, Peres MA, Raymundo Mdos D, Fett R. Sugar content in liquid oral medicines for children. Rev Saude Publica 2005; 39(3): 486-9.
26. Maguire A, Baqir W, Nunn JH.Are sugars-free medicines more erosive than sugars-containing medicines? An in vitro study of paediatric medicines with prolonged oral clearance used regularly and long-term by children. Int J Paediatr Dent. 2007;17(4):231-8.
27. Lussi A, Jäggi T. Erosion—diagnosis and risk factors. Clin Oral Investig 2008; 12(Suppl 1): 5-13.
28. Corrêa MCCS, Lerco MM, da Cunha MLRS, de Arruda Henry MAC. Salivary parameters and teeth erosions in patients with gastroesophageal reflux disease. Arq Gastroenterol 2012; 49(3): 214-8.
29. Wang LJ, Tang R, Bonstein T, Bush P, Nancollas GH. Enamel demineralization in primary and permanent teeth. J Dent Res 2006; 85(4): 359-63.
30. Scatena C, Galafassi D, Gomes-Silva JM, Borsatto MC, Serra MC. In vitro erosive effect of pediatric medicines on deciduous tooth enamel. Braz Dent J 2014; 25(1): 22-7.
31. Kulkarni P, Anand A, Bansal A, Jain A, Tiwari U, Agrawal S. Erosive effects of pediatric liquid medicinal syrups on primary enamel: An in vitro comparative study. Ind J Dent 2016; 7(3): 131-3.
32. Alexandria AK, Meckelburg ND, Puetter UT, Salles JT, Souza IP, Maia LC. Do pediatric medicines induce topographic changes in dental enamel? Brazilian Oral Research 2016; 30(1): 1-8.
مجله دانشکده دندان‌پزشکی اصفهان
دوره 18، شماره 4 - شماره پیاپی 4
دی 1400
صفحه 338-347