مجله دانشکده دندان‌پزشکی اصفهان

رابطه‌ی کاندیدا آلبیکانس و استرپتوکوکوس موتانس با پوسیدگی زودرس دوران کودکی

نوع مقاله : مقاله‌های پژوهشی

چکیده

مقدمه: کاندیدا آلبیکانس می تواند باعث افزایش ریسک ابتلا کودکان به پوسیدگی زودرس دوران کودکی شودو همچنین می تواند پتانسیل پوسیدگی زایی استرپتوکوکوس موتانس را افزایش دهد. ولی اثر این دو میکروارگانیسم بر یکدیگر بر روی پوسیدگی به صورت تجربی به طور کامل ارزیابی نشده است. هدف این مطالعه بررسی رابطه ی کاندیدا آلبیکانس و استرپتوکوکوس موتانس با پوسیدگی زودرس دوران کودکی بود
مواد و روش ها: این مطالعه مورد شاهدی روی30 کودک 6-3 سال (15 کودک دارای پوسیدگی زودرس دوران کودکی و 15 کودک بدون پوسیدگی) انجام شد. نمونه های بزاق غیرتحریکی از کودکان جمع آوری گردید. از محیط کشت کروم آگار کاندیدا جهت تشخیص کاندیدا آلبیکانس و از محیط کشت میتیس سالیواریوس باسیتراسین آگار جهت تشخیص استرپتوکوکوس موتانس استفاده شد. جهت تجزیه و تحلیل داده ها از آزمون های آماری کای دو، من­ویتنی وضریب همبستگی اسپیرمن استفاده گردید(05/0= α).
یافته ها: کلنی های استرپتوکوکوس موتانس در 100% موارد پوسیدگی زودرس دوران کودکی و 26% موارد فاقد پوسیدگی وجود داشتند(001/0>p). همچنین کلنی های کاندیدا آلبیکانس در86% موارد پوسیدگی زودرس دوران کودکی و 13% موارد فاقد پوسیدگی مشاهده شدند(001/0>p).
نتیجه گیری: ارتباط مستقیمی بین استرپتوکوکوس موتانس و کاندیدا آلبیکانس با پوسیدگی زودرس دوران کودکی وجود دارد

عنوان مقاله [English]

Relationship between Candida Albicans and Streptococcus Mutans with Early Childhood Caries

چکیده [English]

Introduction: Candida albicans can increase the risk of early childhood caries in children and can also increase the caries-causing potential of Streptococcus mutans. However, the effect of these two microorganisms on each other on caries has not been fully evaluated experimentally. The aim of this study was to investigate the relationship between Candida albicans and Streptococcus mutans with Early Childhood Caries.
Materials and Methods: This case-control study involved 30 children aged 3 to 6 years (15 children with ECC and 15 without caries). This study was conducted in the Isfahan branch of Islamic Azad University in 2019. Non-stimulating saliva samples were collected from children. Chromagar candida culture medium was used to detect Candida albicans, and Mitis salivarius-bacitracin agar culture medium was used to detect Streptococcus mutans. Chi-square, Mann-Whitney, and Spearman correlation coefficients were used to analyze the data (α = 0.05).
Results: Streptococcus mutans colonies were presented in 100% of cases of ECC and 26% of cases of caries-free children (p value < 0.001). Also, Candida albicans colonies were observed in 86% of cases of ECC and 13% of cases of caries-free children (p value < 0.001).
Conclusion: There is a direct relationship between Streptococcus mutans and Candida albicans with Early Childhood Caries.
Key words: Candida albicans; Streptococcus mutans; Dental Caries; Child

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مجله دانشکده دندان‌پزشکی اصفهان
دوره 20، شماره 4 - شماره پیاپی 4
بهمن 1403