Comparison of Crown Discoloration induced by Clindamycin and Low-Concentration Triple Antibiotic Paste
Document Type : Original Articles
Authors
1 Postgraduate Student of Endodontics, School Of Dentistry, Shahid Beheshti University Of Medical Sciences, Tehran, Iran.
2 Assistant Professor of Endodontics, School Of Dentistry, Shahid Beheshti University Of Medical Sciences, Tehran, Iran.
10.22122/jids.2025.45656.1022
Abstract
Objective:
The aim of this study was to compare crown discoloration induced by clindamycin and low-concentration triple antibiotic paste (TAP).
Materials and Methods:
In this in vitro study, 20 extracted human maxillary anterior teeth were selected and standardized based on buccolingual and mesiodistal dimensions, then randomly divided into two groups (n=10): Group 1 received TAP at a concentration of 1 mg/mL, and Group 2 received clindamycin at 20 mg/mL. The medicaments were placed in the root canals, and teeth were incubated. Tooth color was measured on the buccal surface at the cervical region using a spectrophotometer at 1, 2, and 3 weeks after medication placement, and again 1 month after medicament removal. Data were analyzed using ANOVA.
Results:
In both groups, the greatest discoloration was observed during the first week and gradually increased over time. One month after medicament removal, discoloration continued to increase. The TAP group showed mild discoloration near the perceptibility threshold, while the clindamycin group exhibited less discoloration, below the threshold of clinical detection. No statistically significant difference was found between the two groups (P = 1.00).
Conclusion:
Clindamycin did not induce clinically noticeable tooth discoloration when used as an intracanal medicament. Although low-concentration TAP caused mild discoloration, the difference between the two groups was not statistically significant.
The aim of this study was to compare crown discoloration induced by clindamycin and low-concentration triple antibiotic paste (TAP).
Materials and Methods:
In this in vitro study, 20 extracted human maxillary anterior teeth were selected and standardized based on buccolingual and mesiodistal dimensions, then randomly divided into two groups (n=10): Group 1 received TAP at a concentration of 1 mg/mL, and Group 2 received clindamycin at 20 mg/mL. The medicaments were placed in the root canals, and teeth were incubated. Tooth color was measured on the buccal surface at the cervical region using a spectrophotometer at 1, 2, and 3 weeks after medication placement, and again 1 month after medicament removal. Data were analyzed using ANOVA.
Results:
In both groups, the greatest discoloration was observed during the first week and gradually increased over time. One month after medicament removal, discoloration continued to increase. The TAP group showed mild discoloration near the perceptibility threshold, while the clindamycin group exhibited less discoloration, below the threshold of clinical detection. No statistically significant difference was found between the two groups (P = 1.00).
Conclusion:
Clindamycin did not induce clinically noticeable tooth discoloration when used as an intracanal medicament. Although low-concentration TAP caused mild discoloration, the difference between the two groups was not statistically significant.
Keywords
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